what type of concern/effects is there on a schitzophrenic person taking fluphenazine that didn't have air conditioning and/or was exposed to extreme heat conditions?
Yes, AC may have an effect in older patients.-
There may be a slightly increased risk of serious, possibly fatal side effects (e.g., pneumonia, heart failure) when this medication is used in older adults with dementia. This medication is not approved for the treatment of dementia-related behavior problems. Discuss the risks and benefits of this medication, as well as other effective and possibly safer treatments for dementia-related behavior problems, with the doctor.
Fluphenazine is a typical antipsychotic drug, this means mainly that it can cause more side effects than second generation antipsychotics ( atypical ones, meaning less side effects can be caused by usinf these newer drugs) Like seroquel( quetiapine) zyprexa (olanzapine) and many others.-
Its main use is as a long acting injection given once every two or three weeks to people with schizophrenia who have a poor compliance with medication and suffer frequent relapses of illness.
Notable side effects include akathisia(is a syndrome characterized by unpleasant sensations of "inner" restlessness that manifests itself with an inability to sit still or remain motionless), extrapyramidal side effects, including tardive dyskinesia(is a difficult-to-treat form of dyskinesia (disorder resulting in involuntary, repetitive body movements) that can be tardive (having a slow or belated onset). It is often seen as a side effect of long-term or high-dose use of certain antipsychotic medicines) and Rabbit syndrome(is a rare form of extrapyramidal side effect of antipsychotic drugs in which perioral tremors occur at a rate of 5Hz. Rabbit syndrome is characterized by involuntary, fine, rhythmic motions of the mouth along a vertical plane, without involvement of the tongue) The frequency and severity of extrapyramidal side effects are direct proportional to the dose given and the duration of treatment. Mostly notably, although rare, it can cause hypothermia because it inhibits ability to shiver.
Sedative, allergic-toxic and anticholinergic(is a substance that blocks the neurotransmitter acetylcholine in the central and the peripheral nervous system. An example of an anticholinergic is gabapentin dicyclomine, and the classic example is atropine. Anticholinergics are administered to reduce the effects mediated by acetylcholine on acetylcholine receptors in neurons through competitive inhibition. Therefore, their effects are reversible) /sympatholytic side effects are less likely to occur compared with chlorpromazine(typical antipsychotic ). The direct deposition of fluphenazine in the cornea and retina has so far not been reported.
Neuroleptic malignant syndrome( is a life- threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic drugs. It generally presents with muscle rigidity, fever, autonomic instability and cognitive changes such as delirium, and is associated with elevated creatine phosphokinase (CPK). ), although rare, is a potentially lethal side effect of all antipsychotics.
- Fluphenazine Information for Consumers
- Fluphenazine Information for Healthcare Professionals (includes dosage details)
- Side Effects of Fluphenazine (detailed)
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