I'm struggling with bad anxiety and PTSD. Also had massive heart attack 14 months ago ..had two stents put in. I have been on Seroquel XR for about 9 months at 150mg my doctor has just give me IR for morning 25mg it makes me so down I have to break into quarters. As I'm on Valium and they are trying to get me to reduce but finding it hard..so thought maybe someone else takes both Seroquel XR & IR. Would be great full for help