I got Mirena inserted December 2010 at age 17 frantically after a miscarriage without doing much research. I have noticed weight gain consistently over the past almost 2 years but as for any other side effects? Recently, at the year and 9 month mark I am noticing very tender nipples, major depression, and fatigue like you wouldn't believe. And over the past, since mirena, I've had worse periods than ever before. I'm not sure if I should stick it out or get it removed.