Question about Propranolol & other meds?

Checked on the Interactions Checker & this was reported:

Applies to: propranolol, amitriptyline

MONITOR: Many psychotherapeutic and CNS-active agents (e.g., anxiolytics, sedatives, hypnotics, antidepressants, antipsychotics, opioids, alcohol, muscle relaxants) exhibit hypotensive effects, especially during initiation of therapy and dose escalation. Coadministration with antihypertensive agents, in particular vasodilators and alpha-blockers, may result in additive effects on blood pressure and orthostasis.

MANAGEMENT: Caution is advised during coadministration of these agents. Close monitoring for development of hypotension is recommended. Patients are advised to avoid rising abruptly from a sitting or recumbent position and to notify their doc if they experience dizziness, lightheadedness, syncope, orthostasis, or tachycardia.

Hope this helps? Please take care, best wishes.

Hi, just to put your mind at rest, i have taken these 2 together without any problems. The amitriptyline are good for helping you sleep and relieving your pain at the same time, and used over a period of months (maybe more) you should get good benefits from it. Remember to take it an hour before you go to bed. The propranolol will relax your mind, helping in turn to rid you of so much tension, which again will make your headaches/migranes better. It is a good combination to try.