I've been taking 20 mgs of Adderall XR once a day on week days for 7 months, and recently I've become a little depressed. At first it was just when I was coming off the meds. Then it was most of the time I was on the meds, I mean I could concentrate and the meds were working fine except I was a little depressed. But now I've progressed to being depressed almost all the time, even when I don't take the meds. I'm going to talk to my doc tomorrow. I know depression can be a side effect of Adderall, but I'm curious why I'm depressed even when I don't take the meds, is that normal?