... Venlafaxine 150mg; and I began to be confused, and disoriented. Then I lost my memory. My husband took me to the hospital. The ER Dr's dc'd the Tizanidine, cut my Seroquel to 150mg, and lowered the Baclofen to 10mgs,4xday. Now I am extremely agitated, anxious, and more depressed than usual. Was I taking too many medications that caused the memory loss? I have multiple sclerosis [and trouble sleeping.].