Psoriatic Arthritis - I have lost a significant amount of weight in the last year. Nothing seems to taste good anymore, and I have no appetite. I have heard cancer survivors talk about the problem of nothing tasting good, and it had to do with the digestive track and their chemo drugs, so not sure if there is a correlation?? I take 100 mg Celebrex twice a day, two 25mg Enbrel injections, as well as a weekly .6 methotrexate injections. I am wondering if anyone else is also experiencing similar symptoms?