... prednisone, methotrexate, and celebrex. My stomach has been bothering me and I have been having these pins and needles feelings for a bit now. I just wen to teh doc yesterday and they did some blood work and want to try something else. I have been on these for well over a year now.
Psoriatic Arthritis - Has anyone had any side effects from the meds for Arthritis? I am on humira,?
- Asked
- 9 Apr 2010 by pnevins
- Updated
- 7 November 2018 (10 weeks ago)
- Topics
- celebrex, humira, rheumatoid arthritis, psoriatic arthritis, methotrexate, prednisone, side effect
Details:
Responses (10)
njneuf
9 Apr 2010
It's hard to answer when you don't know what they want to put you on. I was and on methatraxate for almost 5 months now and I have been getting the same pain in my gut(?). My MDput me on a 5 mg dose of Valium which seems to help. Perhaps you can try that.
Hickorynut
9 Apr 2010
pnevins: I personally can not take methotrexate, I tried it for a yr. and finally gave up as my stomach just couldn't handle it anymore. I hv never been on humira, but the people I know who are seem to be very pleased with the results. Prednisone I am on now. 20 mg. for 2 wks. then 5mg. to come off it. I am just doing it for flares that I am having that are out of control. prednisone could very well be your stomach problem. Its hard to say, but hang in there and keep trying, do not give up. How may methotrexate do you take? You may could reduce the number and that may help. It takes a while to find what works. I am on Remicade and it has not worked for me yet.
pnevins
12 Apr 2010
I appreciate your reply. I am on 4 prednisone a day I am down to 4mg but its every day and has been for a while. I take 4 methotrexate once a week. I need to talk to my rheumatologist today and see what he says cuz I feel horrible.
Cheryl hals
7 Nov 2018
What about switching to injections which bypass the stomach?
bousy
10 Apr 2010
Iam on Enbrel for more than 6 months and my case is stable now. Enbrel acts like Humara. I take Enbrel, Arcoxia, Immuran . I feel some times gastric pain so,I take Nexium for it.
amanyhesham_4ever
10 Apr 2010
all artheritis medications causing gastric pain and some making nausea and bad mood
pnevins
12 Apr 2010
Isnt that great that these drugs that help also cause all these other isues. I think Im in a bad mood because I feel like crap all the time.
Thanks
amanyhesham_4ever
12 Apr 2010
pnevins,
yeah it is fact that all drugs have side effects ,but for their benefits we have to take it
i know your feeling very well ,but never give up hope . i had rhumatoid artheritis 3 years ago . not drugs alone ,but also the disease itself causes depression ,but when my case be stable i forget my disease and live normally
with my best wishes
Sacosam
11 Apr 2010
Hello pnevins; Man, if You were on Prednisone and Celebrex at the same time, I do believe I can understand why your stomach's bothering you... let alone mixing those two horrors with methotrexate and Humira, WoW! You need to see a Gastroenterologist asap or you're going to be a very sorry Boy. If you should happen by the office of the Dr. who allowed you to do all those drugs at once, you need to give him a good swift kick. Sacosam
charlyecc
11 Apr 2010
hey sacosam, i totally agree with you on that, i saw all those meds and thought, damn no wonder his gut hurts. there are sum no no's
Sacosam
11 Apr 2010
Hi Charlie; Scary ain't it... but there's worse ! About a week ago, in the Pain Column, there was a Lady doing (6) six drugs... 2 painkillers , a mood stabalizer , 2 anti-depression drugs and a B.P. drug, and she'd been on all of them for over a year! WoW! Sacosam
Avatai
13 Sep 2010
I have RA & the dr putme on prednisone, methotrexate, tramadol, folic acid, zantac. When you are taking prednisone & methotrexate you have to take some type of zantac,nexium,etc. Those will stop the pain with your stomach. You mst take those before you take the other meds. Try seeing you a specialist(rheumatologist) asap! The folic acid goes along with the methotrexate. Good luck! Let me know how things work out for you, ok.
jenone
13 Oct 2010
I am not surprised your stomach has been bothering you. The group of drugs you are taking are very bad news for your stomach. I was taking methotrexate, celebrex, atenolol and nurofen. I already had diagnosed stomach problems - gastritis, ulcerative duodenitis, hiatus hernia and reflux, and was taking Somac for this. My rheumatologist knew all about my stomach problems but insisted I needed to take the methotrexate and celebrex. I stopped the celebrex and nurofen myself, as I couldn't take the stomach pain and reflux any more. Unfortunately, I am still having intense long lasting stomach pain and discomfort from the methotrexate, and I will be asking my rheuamatologist to take me off it. My pain and inflammation is worse, being off the celebrex, but I don't have any options.
jeanlynnvw
12 Jun 2013
My specialist prescribes Nexium to relieve the reflux - I don't have any problems with my stomach and am also on Celebrex, Humira and Methotrexate with folic acid.
MannyKb
13 Oct 2010
I have been on Humira for about 2 years now. No major side effects. Also on MTX, 20 mg. The only problem I'm having is weight gain. Struggling to keep the weight off with exercise. Actually I don't think this stuff is working. I don't feel any worse but I don't feel any better either. I have RA and PSA. Also have a slight stomach pain which I believe is from other meds I take.
I really think you have to weigh the benefits v side effects and then discuss with your doctor. In my case, my doctor told me its time to hang up the Batman costume and buy size 34 pants. The benefits far outweigh the side effects.
Sacosam
7 Dec 2010
Hi pnevins; You mention Psoriatic Arthritis? i've never heard of it... but... I came down with Polymyalgia Rheumatica "PMR" which is a very painful offshoot of osteoarthritis. My Dr. put me on a heavy dose of prednisone for several months , to knock my PMR down to where I could at least walk. As a result, both my upper arms, elbow to shoulder became infected ? "infested"? with Psoriasis which lasted appx. 6 mos. is that what you refer to when you say "Psoriatic Arthritis"! Sacosam
kileyrae
10 Jun 2011
Psoriasis is a common, chronic skin condition that causes red patches on the body. About 1 in 20 people with psoriasis will develop arthritis with the skin condition. In most cases, psoriasis comes before the arthritis.
The cause of psoriatic arthritis is not known, but genes may play a role. In general, people who have psoriasis have a higher rate of arthritis than the general population.
Bo diddly
6 Nov 2018
Celebrex caused me a bleeding ulcer had to stop taking immediately I still suffer from it years later. I recommend you try something else I have AS
Further Information
- Celebrex Drug Information
- Humira Drug Information
- Methotrexate Drug Information
- Prednisone Drug Information
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I have tried the valum as well and that did nothing but make me feel more mellow which was great but the pain didnt go away.
Thanks
For your information
If you have a IPhone, Blackberry or any other phone that gets apps I would suggest that you pay the .99 and purchase MEDSCAPE from WEB MD. They have the BEST interaction checker for you. It has caught reactions that the pharmacy has not. I take 21 pills in the am and 14 at night for my heart, lungs, sugar and all the other things wrong with me from having Vasculitis. Hope this also helps
I'd have to disagree with njneuf. Have you tried the Drugs.com interactions checker?
https://www.drugs.com/drug_interactions.php
I just checked your combinations and there are lots of warnings. You should probably do a check, print out and send to your doctor.
Thats very much. I did go thru the site and it is very good with the interactions. I am going to print this out and send it to my many Dr's today. i wish they would all get together in one room and figure it out but we all know that wont happen.
Your last sentence is the most important. Getting all the doctors on the same page is by far the most important thing you need to do. What I did was ask my primary ruhmy to ask for a time when all the doctors to meet for a conferance by phone. He was able to do this and I attended for the first 10 minutes so I could explain what I felt was wrong. They listened and then I understand that they all agreed to go to a working dinner where I was the topic of discussion. Since that time I further understand that whenever I have an appointment with one of the 4 they schedule a phone conferance.
All I can suggest is that you try it. The worst that can happen is "no" and you may be suprised by the answer.
Also, get a copy of all records from all doctors and make sure that all doctors have a copy of the full packet.
Wow. Thats amazing that they would all do that. My Dr's are at 2 different hospitals though so that may be an issue. As I type im hodl now waiting for the lovely nurse to pick up and give me her attitude. Thanks
My doctors all communicate by e-mail. Whenever I see any of them, they e-mail the others with the problem, diagnosis and medications. I have been on methotrexate for 6 years now, I just found out that when you have to take an antibiotic, you are not suppose to take the methotrexate. I have combined them several times. I learned to always ask when prescribed anything. There is no such thing as a stupid question when it is your health you are dealing with. The pain in the gut, I take the meds with food, that seems to help.