It really depends on why it is being prescribed. I take Provigil for idiopathic hypersomnia and use to take once in the morning and once in the afternoon.
I take Provigil for narcolepsy and cataplexy. My neurologist prescribes it in two dosages: 200 mg upon waking and 200 mg around 11 AM. Provigil is prescribed this way as it has somewhat of a short half life (it doesn't work for many hours). Taking it in two dosages allows me to feel the effects or assistance with staying awake longer into my day. If I understand correctly, 400 mg is the most that can be prescribed in a 24 hour period. So, it is absolutely possible to take more than one dose of Provigil in a 24 hour period as long as the two doses do not exceed 400 mg total.
That being said, it is important to work with your physician to determine what your individual max per day dosage should be by taking into account things like your weight, reason for requiring the medication, etc. Taking too much will absolutely cause some unwanted side effects that can be severe like altered or racing heart, heightened anxiety, essential tremor, etc. In my case, I usually do not truly feel awake until I take the second dose of 200 mg. It is then I feel a true difference and help for daytime sleepiness. I tried another form called NuVigil, and I absolutely felt adverse side effects causing me to need to change medications.
Finally, physicians also have other prescriptions they can use in addition to Provigil depending on your needs. For example, due to my particular presentation of narcolepsy, I need more help than the 400 mg of Provigil provides in order to even function during the day. In addition to my Provigil, I also take 60 to 70 mg of Vyvanse upon waking, which really helped a great deal too. My physician and I went through a trial and error period finding the right additional medication and dose as well. Though I am not symptom free, I am extremely humbled and grateful for finding this medication combination and the assistance it has given to me in my quest to obtain some level of quality of life.
This is my first answer to a question, as I just located this forum today. I am hopeful that you find it helpful, and that I have at least provided you with some more helpful data to research, think about, and ultimately discuss with your physician. Daytime sleepiness for any reason can be crippling and effect every area of your life. I know all too well how overwhelmed and helpless this one symptom can leave you. I sincerely pray that you are able to find the right medication and dosages that you need for your particular situation.
HI- I have NON-24 Sleep/Wake Disorder and can't sleep at night. If I have to function during the day, I take one 200MG tablet of Provigil twice daily - usually one in the morning and one in the early afternoon. Sometimes it does nothing at all, sometimes it helps me be more awake and productive, and sometimes it makes me feel a bit jittery. Adderall (20MG tablet twice daily) actually works better for me and is MUCH less expensive ($8 vs. $50 with insurance, $55 vs. $1,400 without for 60 pills). Unfortunately, because it such an abused drug my doctor stopped prescribing it. Very unfair, aggravating, and costly to those of us that used it only as prescribed. Hope this helps:)
- Provigil Information for Consumers
- Provigil Information for Healthcare Professionals (includes dosage details)
- Side Effects of Provigil (detailed)
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