I started taking Wellbutrin six says ago (XL 150) , complicated by being 7 days Pristiq free. I have everything from paranoia, anxiety, to phase shifting in my brain,leg cramps, nausea, diarrhea, hot flashes, insomnia, yada yada yada... and of course it is hard to determine which is from the well known gnarly Pristiq withdrawal and which is from Wellbutrin.

However, one thing I noticed is that I feel particularly bad after I take the dilaudid I take daily for chronic nerve pain. I take 1mg at most 2-3 times a day.

Is there a known interaction between dilaudid and Wellbutrin?