I started taking Pristiq about 4 months ago for severe anxiety/depression and have slowly moved up in dosage to the maximum now of 200mg. I have found that the first 2 - 3 weeks I get an initial boost of motivation, peace, and in general some normality and I believe that things will be ok. After that 2 week mark it is like the effects wear off and I am back to a daily continual struggle. I have just passed the 2 week mark at 200mg and this weekend I experienced a fairly big downturn that has me feeling nearly as bad as when I first started the medication. I am quite aware of my mental health, see a psychologist, and try mindfulness strategies but am concerned that there is no way out. Should I continue with the 200mg and give it more time or what would be your suggestions?