Hello, motherinlaw is 87, lives in asst living, suffers from dementia, depression and anxiety. Psychiatrist had her on different brands now on Pristiq. Does not work. Increased it in Dec. She is depressed everyday, all day. Has no desire to leave her room. Cries all day. He said he cannot do any more for her. She refuses to get dressed for breakfast, but occasionaly surprises us and does but not often. Is there anything else that he is missing? The NP at the asst living said that Pristiq rarely works for elderly. Your input is appreciated as we are all frustrated.