Hi, O! Some people begin to feel a little better at about four weeks, but it can tak 6-8 to reach therapeutic levels in your bloodstream. Chances are you'll be feeling better very soon but if after another few weeks things are still not good enough talk to your doctor, explain that you're still depressed, and ask about a possibly dosage increase. The maintenance dose for some folks is as high as 400mg daily so you have lots and lots of room.
Best wishes! WCV
PS, we're just regular folk but we'll be happy to share advice and personal experiences if that might help.
- Pristiq Information for Consumers
- Pristiq Information for Healthcare Professionals (includes dosage details)
- Side Effects of Pristiq (detailed)
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