I had a stroke in Oct '11, and heart surgery in Dec '11. My doctor said I need to be on Plavix + Aspirin until June '12. And not to get pregnant before Sept '12. But - our birth control methods have failed evidently. Does anyone know about the risks of (a) being on Plavix through the first trimester (b) Carrying a pregnancy to term with an only-partially-closed hole in my heart?
Needless to say you are a very high risk patient. I would suggest that you find a hematologist that will work with your ob/gyn and cardiologist. You should request that the hematologist do a full blood workup to ensure that you do not have any blood disorders. This should help you understand why you had the stroke as well. If you and your medical team decide to continue with your pregnancy you will probably be required to stay at home or more likely stay in the hospital for your last trimester. This is what happened to my daughter-in-law even though she had her hole fully repaired before she got pregnant. They will not want you to do any kind of work since you still have a hole in your heart.
There is no evidence of impaired fertility or fetotoxicity due to Plavix. However, Plavix should be used during pregnancy only if clearly needed. You should thoroughly discuss this with your medical team. Studies in rats have shown that Plavix and/or its metabolites are excreted in the milk. It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from Plavix, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Hope this helps. Good luck.
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