... and I am 19 weeks pregnant... Does anyone know if this is safe for my baby? I read that macrodantin (nitrofurantoin) is an antibiotic that is used to treat things like streptococcus , staphylococcus, and E-coli? That freaks me out ... can anyone help?
The FDA uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category B is given to medicines that have not been adequately studied in pregnant humans but do not appear to cause harm to the fetus in animal studies.
In most animal studies, large doses of nitrofurantoin (the active ingredient in Macrodantin) did not cause any problems during pregnancy. One animal study suggested that extremely high doses might be linked to poor growth and minor birth defects, but such problems were not seen with lower doses, which were still higher than those used in humans.
Another study suggested that high doses of nitrofurantoin may cause lung tumors. It is unclear what exactly the results of these animal studies mean for human use of the drug.
It should be noted that problems seen in animal studies (which often involve very high doses of the medication for long periods) do not necessarily reflect what happens with humans. Pregnant women can be assured that nitrofurantoin products such as Macrodantin are some of the most commonly used antibiotics for urinary tract infections in this situation.
Cephalexin is also a Pregnancy Category B which do not cause side effects to the fetus in animal studies but that have not been tested in pregnant women.
However, it is important to note that animals do not always respond to medicines the same way that humans do. Therefore, a pregnancy Category B medicine may be given to a pregnant woman if the doc believes that the benefits to the mother outweigh any possible risks to the unborn child.
It would always be recommended to talk to your gynecologist for more accurate info, since you are 19 weeks pregnant.
Please take care, look after yourself & the unborn baby, best wishes.
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