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Pregnancy - is esomeprazole safe in 1st trimester?

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Inactive 9 Mar 2013

Esomeprazole Pregnancy Warnings

Esomeprazole has been assigned to pregnancy category B by the FDA. Animal studies have failed to reveal evidence of teratogenicity or fetal harm at therapeutic doses. However, doses of 5.5 to 56 times the human dose on a body surface area basis have produced dose-related embryolethality and fetal resorption. There are no controlled data in human pregnancy. Esomeprazole is only recommended for use during pregnancy when benefit outweighs risk.

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