I am 3 days into starting duloxetine for SFN. I was taking pregabalin, but this needed to be changed due to sensitivity. I am finding things really difficult through the medication change. I don't know if it's side effects of the new medication, or withdrawal from the old. This is the 4th change of medication in the last 6 months and I do t know how much more my body will take. This is truly affecting my life, I know it's early days, but if anybody out there has a positive experience moving from one medication to another that would be great.