Have been taking increasing doses of prednisone 10 to 20 mg/day for control of back joint pain. I have found that on the occasions when I have needed a medrol pack my pain is gone for several days. It is my understanding that prednisone is converted to the usable Methylprednisilone by the liver. Is it possible that my liver is not converting, or at least not well, that transformation to methylprednisilone. I am considering trying the converted potency dose to methylpred to see if that works better and maybe be able to reduce (over time) the overall dose.
Prednisone is a very powerful drug, it is actually very scary to me. I have a Master's in Nursing and I have seen what long term use of prednisone does to one's adrenal glands. Have you had your adrenal function checked lately. Also, have you tried opiates for the control? I find them really helpful and only get prednisone shot into my epidural space every 6 months.
Talk to the doc regarding tapering prednisone now, hopefully before you require it to live (like JFK). Opiates used with the help of a pain management doc will do wonders for your pain, although Oxycontin doesn't work for me since 'whoever' changed te formulary. I titrate oxycodone to my pain level as it only lasts 4 hours (usually 15 in the am and 7.5 thru the day... I break the 15s and take as needed, not more than 60 mg every 24 hours.
Good luck in your life adventures,
The Sweetest Hippie/Flower Child ;-)
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