... diagnosed... with a lung disease. Part of the treatment is prednisone. My dr started me on 40 mg daily for a month. I'm tapering off and I've suffered from the typical side effects, moon face, weight gain, profused sweating, irritability, etc. I am wondering if anyone has experienced feeling extreme anxiety and fatigue at the same time. I don't know if its from my other meds not playing well with the prednisone. I am so tired, but anxious all the time. I am almost non functional. I can go days without showering, brushing teeth, changing clothes, etc. Simple chores, washing dishes, sweeping floors, etc. Any comments, suggestions,etc?