I've been on Pred. for 11 yrs for PMR. Had every side effect including osteonecrosis (THR), cataracts, hypertension, weight gain @ so on. When I wean down to 1mg the PMR flares up again. I try to tough it out but have to go back up again to 5mg. I've been up & down this roller coaster for yrs now. I hate this Med. It should be banned! 2 yrs ago I was DX with Lung cancer. I really think Prednisone was the cause because of my immune system being compromised. Get off this drug-it will kill you.