The effect of corticosteroids on oral anticoagulants (e.g., warfarin) is variable. There are reports of enhanced as well as diminished effects of anticoagulants when given concurrently with corticosteroids; however, limited published data exist, and the mechanism of the interaction is not well described. High-dose corticosteroids appear to pose a greater risk for increased anticoagulant effect. In addition, corticosteroids have been associated with a risk of peptic ulcer and gastrointestinal bleeding. Thus corticosteroids should be used cautiously and with appropriate clinical monitoring in patients receiving oral anticoagulants; coagulation indices (e.g., INR, etc.) should be monitored to maintain the desired anticoagulant effect. During high-dose corticosteroid administration, daily laboratory monitoring may be desirable
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
Posted 2 Sep 2009 • 1 answer
4yr old is taking prednisolone liquid with ranitdine its a strong taste having trouble swallowing it
Posted 5 Sep 2009 • 1 answer
Posted 18 Oct 2010 • 1 answer
If prednisolone tablet will take for a long period, Is it get any problem in Kidney,Heart, Lungs Or?
Posted 11 Feb 2012 • 2 answers
Posted 9 Feb 2016 • 0 answers