... in remission. Knowing the long term side effects of PPIs, I tried to go off it and started taking natural remedies like DGL and Apple Cider Vinegar. It worked for about 2 days. Yesterday, after taking the ACV before meal for the first time, I experienced the worst heartburn in almost 10 years. I quickly took my Dexilant and I am feeling better today. I want to go off PPI, but it seems that I don't have a choice. Can anyone suggest, how to go off this medication? I went off cold turkey and that probably was the mistake. Thanks for your input