... despite increase, feel very flat and low and sad and black and hopeless
It is possible for a medication of this nature to lose some effectiveness. You may need a further increase in dosage if possible or possibly switch to a different antidepressant. There is a newer version of venlafaxine available now called Ptistiq (desvenlafaxine). Might want to discuss these possibilites with the prescribing doc.
- Venlafaxine Information for Consumers
- Venlafaxine Information for Healthcare Professionals (includes dosage details)
- Side Effects of Venlafaxine (detailed)
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