I take Humira for psoriatic arthritis; primary targets are hands, feet, neck. After only a month (two doses), I'm convinced it's working on my cervical spine. In situations where it would have been quite painful and debilitating, it just wasn't. But my hands and feet are still quite involved. Is it possible/likely that Humira works at different rates in different parts of the body or different levels of disease? In other words, do I have a reasonable hope that it will still offer some relief for my hands and feet? Thanks much for helping; no matter which way the answer goes, it will help to know what to expect.