Please define the exact action of drug in the system?
- 26 Oct 2009 by veonicasimmons
- 9 November 2009
Celebrex (celecoxib) is a nonsteroidal anti-inflammatory drug that exhibits anti-inflammatory, analgesic, and antipyretic activities in animal models. The mechanism of action of Celebrex is believed to be due to inhibition of prostaglandin synthesis, primarily via inhibition of cyclooxygenase-2 (COX-2), and at therapeutic concentrations in humans, Celebrex does not inhibit the cyclooxygenase-1 (COX-1) isoenzyme. In animal colon tumor models, Celebrex reduced the incidence and multiplicity of tumors.
The pharmacodynamic and pharmacokinetics are also stated in the link below.
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