Hi, I have been taking Prozac (Fluxetine20) but recently I had Angioplasty and I have to take Plavix for at least one years. But I've read that plavix and prozac have drug interaction. (Prozac lower the effect of plavix). I searched for other antidepressants (ssri's) such as Effexor and Citalopram, but they increase the risk of bleeding. I'll be grateful if u help me what drug can I take. Is Prozac 10 harmful too? Tnx alot
Only your doctor can weigh the risks vs benefits of the medications. As you mention many other SSRI's induce bleeding possibility. My mother takes Plavix and Lexapro successfully, but increased bleeding is possible. There is another antidepressant called Wellbutrin. Plavix increases the blood concentration of Wellbutrin so dosage must be adjusted, but doesn't have the bleeding potential. Just a thought to ask the doc.
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