I am not sure what you are asking, it got cut off. Marcaine and epinepherine injected as a local can cause systemic effects. Some people are sensitive and will experience increased heart rate, feel jittery, have rapid respirations etc. When I worked surgery we often had people say they were allergic to "caines" and on further questioning you find out that it is actually a reaction to the epi and not the anesthetic. This often happens in the dentist offices and dentists do not have the knowledge that anesthesiologists do.
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