I have been on a multitude of antidepressants over the years with no positive results just negative ones. Depression runs in my family too and is ruining my marriage. Last week we changed my anti-depression one again. I've been changing them for 10 years now. He also gave me a script for tramadol for shoulder and back pain it really helped with my depression too. I'm considering asking him for a larger script of tramadol. Hopefully he agrees. Anyone have suggestions on how to talk with him?