I was on 50 mg of Zoloft from May 2015-mid January 2016. Stupidly decided to go off it. 3 months later on April 15 I went back on it. I had been on it 2 years before with no side effects. Normally my doctor eased me back on it by starting me off with 25 Mg But told me to take 50 mg instead. Well only a week on the 50 and my body freaked out, was having heart poundings and waking up panicked. Dealing with depersonalization as well. Went to the doctor asap. She put me on 10 mg of Paxil. Day 3 of Paxil I felt like I wasn't even alive, total zombie mode, emotionally numb. Decided to take 25 mg of Zoloft that day instead. Is this going to mess up my system? I just can't handle the emotional numbness of the Paxil. I think my body just needs to be eased back onto the Zoloft.