I don't find them very effective and have told my psychiatrist that I'd really like to be off antidepressants since my depression is related to whether I'm having panic attacks or not. I'm also on Klonopin which so far seems to be the most effective med. However, now I'm on two new anti depressants and tapering the Klonopin. Doesn't seem to make sense. I'd like to hear your experiences please.