I have been taking 10mg Lorcet, 6 daily for 8 yrs. Obviously, this stopped working so well. Now my doctor added Nuncynta 75mg 3 times daily for severe & break-through pain. I forgot to ask, how to dose for break-through pain? Together okay or always separate? Also, yes, I am edgy on Nuncynta & when it wears off, I feel depressed or less happy, per say. Take another & it leaves, so it must be the Nuncy. I also was on Lamictal, but I don't know if I should take them together? I feel as if my neck is sweating (happens at night too), but it isn't. Odd. Any advice on dosing for break-through, please?