Serious adverse reactions which may be associated with OxyContin Tablet therapy in clinical use are those observed with other opioid analgesics, including respiratory depression, apnea, respiratory arrest, and (to an even lesser degree) circulatory depression, hypotension, or shock.
The non-serious adverse events seen on initiation of therapy with OxyContin are typical opioid side effects. These events are dose-dependent, and their frequency depends upon the dose, the clinical setting, the patient’s level of opioid tolerance, and host factors specific to the individual. They should be expected and managed as a part of opioid analgesia. The most frequent (>5%) include: constipation, nausea, somnolence, dizziness, vomiting, pruritus, headache, dry mouth, sweating, and asthenia.
In many cases the frequency of these events during initiation of therapy may be minimized by careful individualization of starting dosage, slow titration, and the avoidance of large swings in the plasma concentrations of the opioid. Many of these adverse events will cease or decrease in intensity as OxyContin therapy is continued and some degree of tolerance is developed.
Clinical trials comparing OxyContin with immediate-release oxycodone and placebo revealed a similar adverse event profile between OxyContin and immediate-release oxycodone. The most common adverse events (>5%) reported by patients at least once during therapy were:
You can read more by going to Drugs A to Z 7 typing name of drug she was given, Oyxcontin is different than Oxycodone, so you need to do some research, Good luck to you & I hope you mother gets better & in a happier place... (OPPS! guess there's more!)
The following adverse experiences were reported in OxyContin®-treated patients with an incidence between 1% and 5%. In descending order of frequency they were anorexia, nervousness, insomnia, fever, confusion, diarrhea, abdominal pain, dyspepsia, rash, anxiety, euphoria, dyspnea, postural hypotension, chills, twitching, gastritis, abnormal dreams, thought abnormalities, and hiccups.
The following adverse reactions occurred in less than 1% of patients involved in clinical trials or were reported in postmarketing experience.
Blood and lymphatic system disorders: lymphadenopathy
Cardiac disorders: palpitations (in the context of withdrawal)
Ear and labyrinth disorders: tinnitus
Endocrine disorders: syndrome of inappropriate antidiuretic hormone secretion (SIADH)
Eye disorders: abnormal vision
Gastrointestinal disorders: dental caries, dysphagia, eructation, flatulence, gastrointestinal disorder, ileus, increased appetite, stomatitis
General disorders and administration site conditions: chest pain, edema, facial edema, malaise, pain, peripheral edema, thirst, withdrawal syndrome (with and without seizures)
Hepatobiliary disorders: cholestasis
Immune system disorders: anaphylactic or anaphylactoid reaction (symptoms of)
Infections and infestations: pharyngitis
Injury, poisoning and procedural complications: accidental injury
Investigations: hyponatremia, increased hepatic enzymes, ST depression
Metabolism and nutrition disorders: dehydration
Musculoskeletal and connective tissue disorders: neck pain
Nervous system disorders: abnormal gait, amnesia, hyperkinesia, hypertonia (muscular), hypesthesia, hypotonia, migraine, paresthesia, seizures, speech disorder, stupor, syncope, taste perversion, tremor, vertigo
Psychiatric disorders: agitation, depersonalization, depression, emotional lability, hallucination
Renal and urinary disorders: dysuria, hematuria, polyuria, urinary retention, urination impaired
Reproductive system and breast disorders: amenorrhea,decreased libido, impotence
Respiratory, thoracic and mediastinal disorders: cough increased, voice alteration
Skin and subcutaneous tissue disorders: dry skin, exfoliative dermatitis, urticaria
Vascular disorders: vasodilation