... after discontinuing the pill and after only taking it for four days. how long does it take for the med to wear off?
Risperidone and its metabolites are eliminated via the urine and, to a much lesser extent, via the feces. As illustrated by a mass balance study of a single 1 mg oral dose of 14C-risperidone administered as solution to three healthy male volunteers, total recovery of radioactivity at 1 week was 84%, including 70% in the urine and 14% in the feces.
The apparent half-life of risperidone was 3 hours (CV=30%) in extensive metabolizers and 20 hours (CV=40%) in poor metabolizers. The apparent half-life of 9-hydroxyrisperidone was about 21 hours (CV=20%) in extensive metabolizers and 30 hours (CV=25%) in poor metabolizers. The pharmacokinetics of risperidone and 9-hydroxyrisperidone combined, after single and multiple doses, were similar in extensive and poor metabolizers, with an overall mean elimination half-life of about 20 hours.
It takes 5.5 x elimination half lifes for a medicine to be cleared from the system. If we use 20 hours as the mean half life of risperidone, it'll take 110 hours i.e. approx 4.6 days (5.5 x 20 hours) for it to be out of ones system.
- Risperidone Information for Consumers
- Risperidone Information for Healthcare Professionals (includes dosage details)
- Side Effects of Risperidone (detailed)
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