I had Orencia infusions for 3 years and it worked wonderfully. I had to stop it (or any biologic) in November 2017 after being diagnosed with breast cancer. I had a double mastectomy in July 2018. RA symptoms returned slowly but surely and are now worse than ever. I just had first infusion of Orencia Dec 6, 2018. Has anyone else taken it again after long break and did it work? I of course realize it could take a couple of months or so again. I have not had chemo or radiation for the breast cancer. Any thoughts or experiences with this question would be much appreciated!