... 15 mgs of oxycodone to 5 mgs. 3 times a day. I take Nucynta 100 mgs ER two times a day. My pain never lessens below an 8 or a 7. Is there a solution for me? I take LORAZEPAM 3 times a day as needed. My Dr. tells me he cannot increase my meds because of my age and I am on oxygen. ... 1 1/2 Liters. Also, I am one of those patients that medicine works opposite on me. Very hard to find a pain medicine that works. Can you help? Thank you.