Unfortuately I have has RSD in my leg for 12 years. I finally went to a pain management center as my Doctor has prescribed Norco 7.25/325 five max a day for 8 years and it isn't effective, even with a max amount of Lyrica. PM is putting me on Nucynta 100mg twice a day mixed w Norco pills to see how effective the 100mg Nucynta is before increasing dosage. I'm asking for any input or thoughts.