I've been on trintellix 10mg for 8 weeks, working my way up and it seemed like it was maybe working a little bit, well it was more than i realized and all of a sudden one day everything I struggled with before was back just as bad as it had been before i started it.. is it normal for these meds to maybe not always work every single day or what.. I'm just worried its completely stopped working. Thanks
Is it normal for antidepressants to stop working for a few days?
- Asked
- 8 Dec 2018 by Jgo94
- Updated
- 9 December 2018 (11 weeks ago)
- Topics
- depression, anxiety, stress, antidepressant, ssri, trintellix, antidepressants
Responses (1)
Hello Jgo:
It is not unusual for a patient to experience a resurgence of depression or anxiety in the early stages of treatment. However, some stability in mood should occur 8 weeks or so into therapy. Are you still struggling with depressive episodes? This too could be an indication that your dosage needs to be increased to 15 mg. Remember to avoid the use of alcohol or other recreational while using anti-depressants - particularly in the early stages of treatment.
Take care for now and all the best.

Further Information
- Trintellix Information for Consumers
- Trintellix Information for Healthcare Professionals (includes dosage details)
- Side Effects of Trintellix (detailed)
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