I have interstitial cystitis. Bladder botox helps the frequency and urgency... but I still have constipation and pain. Dr. put me on MagOx for constipation. I take Norco for chronic pain from previous auto accident. Those are the only meds I take. I have had no appetite for almost 2 weeks. I eat a little bit to keep from losing too much weight but am not hungry and usually get a stomach ache from eating. I am still losing weight.