I was diagnosed with Bi Polar Dissorder when I was 32 I will be 59 3/13. I started out on Lithum for a number of years and was switched to Depokote 2,000mg per day. I get regular blood levels but it dosn't tell me how my liver is doing. Started Oxycodone 5mg with 325 mg /APAP 4 times a day which the 325 APAP worries me for potenial liver damage. I started it today would anyone know my possible risk for damage to my liver. I hear the APAP is more dangerous than the Oxycodone. I am now down to 1,500 mg Depakote the cumlative effect worries me.
New Member Can Use of Depakote Cause Liver Damage?
- 22 Feb 2012 by sedrickusa
- 11 April 2012
- depakote, bipolar disorder, blood disorders, liver
Added 25 Feb 2012:
It is the APAP 325 that has me concerned it adds up to 1,300mg per day wouldn't you think that is a rather high dose combined of Acetaminophen Extra Strength aprox = 2and1/2 caplets 7 days a week plus 1,500mg Depokote. just seems to me that the combination 7 days a week could have potential damage to my liver. I am satisified with the answers I got with regular blood tests any problems would become evident. I have heard it said that taking Acetaminophen on a prolonged basis can be harmful. For now I am not going to lose any sleep over it. Matter of fact I feel pretty sleepy now and going to bed. Thanks
If you are concerned, then have the doctor run some simple blood tests to determine your liver function. The test can be run on the same draw when you get your other blood levels checked. I wouldn't be too concerned but having your liver checked is always a good idea.
Most regular docs run a liver panel & it will show as alk. phospastes, ALT & AST. Ask for a copy of your test results, & you should see if that is listed. If they gave your results via phone, I am sure if the levels were too high, they would have told you so...
If you are taking Depakote your Dr. should already be doing regular checks of your liver function due to the fact that Depakote can effect your liver function. Although I don't know about the cumulative effects, as long as you are going in for your regular check-ups you should be ok. But I do agree that you should ask for a copy of your blood work. The results are usually pretty easy to read because they generally list the normal range next to your level. Hope this helps.
- Depakote Information for Consumers
- Depakote Information for Healthcare Professionals (includes dosage details)
- Side Effects of Depakote (detailed)
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