.My son has been taking 0.1 mg of Clonidine for several years now, but the white one from Mylan I believe, now I just got a 90-day supply from my mail order company of Actavis which is a lot smaller and orange. I verified that it is the same medication, but since he started taking this one he hasn't been sleeping as well and has been more aggravated which is why he takes it in the first place. Has anyone on here recently be changed from another generic to the Actavis one and noticed that it isn't working as well? I take Topomax and when it went generic I got stuck with a 90-day supply of Topirimate by Actavis and the pills were about 1/2 the size of the name brand ones, tended to fall apart in the bottle, tasted nasty, and didn't work at all. I had to go to Brand name only. Then just recently I saw another generic form of Topirimate and it looked a lot better and I may try it. I'm just wondering if anyone out there has seen a significant difference going from one brand or generic to Actavis