... higher doses of sinemet cr they continue to increase. this is the only PD med that she takes and did great on the lower levels. They recently put her on nine 50 -200 mg at every 2 1/2 hours and a few nightly one every three hours. Any opinions or personal experience at these levels??? They want me to increase to 13 over the next 8 weeks. She has been having increased anxiety attacks as we increase, followed by terrible weekness and feel like she is going to die. Makes me hesitant to keep increasing since I am thinking she is actually getting overmedicated. How would I even begin to question a highly reputable neurologist about it without causing trouble.