Checked the Interactions between the 2 meds, and it has been recommended to be monitored:
Applies to: Lipitor (atorvastatin), Valturna (aliskiren/valsartan)
MONITOR: Coadministration with atorvastatin may increase the plasma concentrations of aliskiren. The exact mechanism of interaction is unknown but may involve competitive inhibition of the CYP450 3A4 metabolism of aliskiren. According to the product labeling, peak plasma concentration (Cmax) and area under the concentration-time curve (AUC) of aliskiren were increased approximately 50% by atorvastatin following multiple dosing. Aliskiren had no significant effect on the pharmacokinetics of atorvastatin.
MANAGEMENT: Caution is advised during coadministration of aliskiren with atorvastatin. Antihypertensive response should be monitored more closely following initiation, discontinuation, or change of dosage of atorvastatin in patients who are stabilized on their aliskiren regimen. Patients should be advised to notify their physician if they experience excessive adverse effects of aliskiren such as dizziness, lightheadedness, diarrhea, abdominal pain, and gastroesophageal reflux.
Please for technical details talk to the doc who prescribed the med, hope the info helps?
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
Have severe muscle pain after 6+ yrs using lipitor.It takes wks to get appt with doc.Can I stop now?
Posted 30 Jan 2010 • 1 answer
My mom has headaches & dizziness from valturna as precribed by her doctor- should she stop using it?
Posted 15 Feb 2011 • 1 answer
Posted 20 Sep 2012 • 1 answer
Posted 1 Jan 2013 • 2 answers
Posted 25 Aug 2016 • 0 answers