... through the kidneys like the Oxycontin he is currently taking, is this true? If this is true about the Opana it would be much better and safer for him to take than the Oxycontin ER he is currently taking as it does filter through the kidneys. Can anybody tell me if this is true about the Opana ER or IR not going through the kidneys like we have been told? If anyone knows for sure about this I would greatly appreciate it if they would tell me! Thank you from Curiouscatwoman
Opana is primarily metabolized by the liver though some of the metabolites are excreted in urine. The literature states the following for reanl impairment and Opana ER (oxymorphone ER):
In a study of extended-release oxymorphone tablets, patients with moderate to severe renal impairment were shown to have an increase in bioavailability ranging from 57-65%. Such patients should be started cautiously with lower doses of Opana and titrated slowly while monitoring for side effects.
So there is still some risk but not as much as with the oxycontin.
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