did not work alone, only in conjunction with Relpax. Now she was put on Dihydroergotamine Mesylate injections. The direct line (Pic line) worked well for about two weeks, now she gets headaches again despite injections every 8 hours. What is the explanation? Does she need more patience or is it the wrong medication? The injections were supposed to wean her off the Relpax. Anybody has an answer?