... been opening the capsules and putting the contents in a drink for her. A pharmacist had said it was alright to open the capsule, and just to not crush the pieces (like tiny beads) inside. Now I've heard that this shouldn't be done, and the capsules should never be opened since the time-release feature is affected. How do time released medicines work? I would guess that the "beads" inside would be different sizes or colors so some would become active sooner than others. But all of the beads look the same. The ingredient in Aggrenox, called dipyridamole, needs to be taken evenly throughout the day and night. So without the time-release feature, as a tablet that could be crushed, it has to be taken every few hours around the clock which isn't always easy to do