Do Monoamine Oxidase Inhibitors (MAOi) work on Obsessive Compulsive Disorder?
- 22 Nov 2012 by empire5sb
- 18 Nov 2014
- nardil, parnate, anxiety, obsessive compulsive disorder, generalized anxiety disorder, antidepressant
Are MAOis useful in helping those with severe anxiety, particularly those with OCD? I was doing research on antidepressants and came across MAOi specifically Nardil & Parnate.
I have severe Anxiety and OCD. Ive tried Zoloft (worked but pooped out), celexa, Prozac, Luvox, Viibryd, and anafranil (tricyclic) with no success.
I suffer from the same conditions as you (I empathize with you), and also I am manic depressive, been on meds more than half my life, I am 44 years old.
Obsessive-compulsive disorder (OCD) is an anxiety disorder characterized by unreasonable thoughts and fears (obsessions) that lead you to do repetitive behaviors (compulsions).
Antidepressants that have been specifically approved by the Food and Drug Administration (FDA) to treat OCD include:
-Paroxetine (Paxil, Pexeva)
Source: Mayo Clinic.
Also Effexor and Wellbutrin.
Hello empire5sb. No. MAOI's are not perscribed for OCD. There was a point some years ago, it was tried and there was little or no improvement in regards to OCD. Best of wishes, pledge
I also have anxiety, depression and OCD, on and off fror 20 years or so.
Parnate (Tranylcypromine) has definitely been the best medication I have ever taken... it has turned my depression around, and has definitely helped my OCD a lot (more than any other drug I've tried). But thats just me... everyone is different.
I do struggle with side effects though... it's quite a tough medicine to take, so be prepared for that side of it too.
in the feeling good handbook by dr david burns, he says "patients with recurring obsessive thoughts and compulsive ritualistic, nonsensical habits may also experience relief when treated with maoi s."
I take Nardil for depression but I do not have OCD. I have some anxiety but also take Ativan. I wish I could be of more help. If your doctor is not helping maybe you need to find a new doctor. Just a thought. If good stick with your present one. Good luck.
I took Parnate (for anxiety & OCD) and ended up in the ER about 8 weeks into it. I followed ALL directions and avoided the food I was supposed to. It caused me more anxiety being scared to death that I might eat or drink something "bad". I still don't know what caused my hypertensive crisis. My doctor had me taper off of it and quit taking it. Although it helps many, many people, it was a wrong fit for me. Hopefully you will have more luck with it.
I started taking Nardil 25 years ago for severe anxiety disorder (social phobia) after trying nearly every antidepressant on the market. Nardil turned my life around. I also have Bipolar Disorder, so I take a few other meds as well. MAOI's tend to work specifically well for a range of anxiety disorders. About 4-years ago I moved so had to get a different doctor. He was shocked that I was on Nardil and talked me in to trying something else. Nada, nothing worked went back to Nardil and life is good again. Usually MAOI's are prescribed as a last ditch effort because of potential side effect of hypertensive crisis if one ingests foods/medications with a high level of tyramine. aged cheese, liver, fava beans, etc... In 25 years I have never had a hypertensive episode and I've got to admit I eat a lot of stuff I'm not supposed too.
They have a transdermal MAOI patch out now. the food/medication restrictions are a lot less I have heard. good luck to you. you might check out the support/info groups on this site Nardil and Phenlyzene <-I didn't spell that correctly. I'd listen to people that have taken the drugs rather then looked them up online and given the info they find. good luck~
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