Glimepiride primarily lowers blood glucose by stimulating the release of insulin from pancreatic beta cells. Sulfonylureas bind to the sulfonylurea receptor in the pancreatic beta-cell plasma membrane, leading to closure of the ATP-sensitive potassium channel, thereby stimulating the release of insulin.
- Glimepiride Information for Consumers
- Glimepiride Information for Healthcare Professionals (includes dosage details)
- Side Effects of Glimepiride (detailed)
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