My mother is on alprazolam, just recenty prescribed Zoloft (she had bowel obstruction surgery in April and wound is not healing properly). She says she cant sleep and her mind won't shut down, she worries that she will never get her health back again. She is 82. Now one of her drs prescribed mirtazapine to help her sleep. I'm concerned she is on way too many drugs. Any interactions between the 3? she doesn't want to take mirtazapine because she read that it too is an anti-anxiety and she knows that alprazolam 0.5mg(taken 3x daily) is also the same type of drug. She is also on COPD meds, I believe spirea. HELP!
Hello Redski. The two can be taken together. There are CNS warnings but this combination is a common one. Mirtazapine is an anti-depressant and not perscribed that often for anxiety. It will help her sleep (I take Mirtazapine for sleep) Her age is a factor but I believe that the Mirtazapine will be at a low dose. Regards pledge
mirtazapine is an antidepressant. If its combined with zoloft, another anti depressant she may have some side effects. She is probably not clearing meds as well as she used to, so they can be in her system longer. The xanax added could really make her sleepy and possibly have trouble breathing. I wonder if all her docs know every med she is on. Does she use the same pharmacy? It would lessen her chances of getting meds that might interact. I agree with you, it would not be a good idea to add the mirtazapine to the mix. Has she tried something like benadryl for sleep? Sometimes something as simple as 2 tylenol and a glass of milk at bedtime helps.
I'm also prescribed alpralozam [.5mg] and mirtazapine. I asked my doctor the same question, since I knew how drowsy the mirtazapine made me and was concerned about having slowed breathing etc... but my doctor only said that I should try to avoid taking them at the same time, especially before going to sleep; so this might be even more relevant to your mother since she has COPD. He also said that the less mg. of mirtazapine I take the drowsier I'd get, which I thought was odd but turned out to be true. I'm only 27 and also not on Zoloft, but just thought I'd let you know that I haven't had any issues with these two prescriptions.
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