Just had Mirena put in 3 days ago. Not too painful, just uncomfortable. The cramps have been awful ever since! No bleeding, spotting, just bad cramps. Had been on Depo for 18 years and have 2 grown kids (both vaginal births). Granted, I haven't had period cramps in a long time, but I don't remember them being this bad! I can't continue to miss work and be flat with the hot pad for so many days. Will it end soon? Maybe staying on Depo wouldn't have been so bad. Doc said that it was working against me at age 46, as far as weight and bone density issues. I figured the bonus of not having periods and mirena lasting 5 years, that it would take me right into menopause. So far though, these cramps are making me second guess my decision.