Minocycline - Is it effective for use in OCD patients?
- Asked
- 27 Mar 2016 by Anonymous
- Updated
- 5 June 2016
- Topics
- obsessive compulsive disorder, minocycline
Responses (1)
masso
27 Mar 2016
No, minocycline is an antibiotic , it belongs to the drug class of tetracyclines.
It is used in the treatment of acne; bacterial infection; skin or soft tissue infection; rheumatoid arthritis; bartonellosis.
https://www.drugs.com/minocycline.html
Click on the link for a list of OCD medications:
https://www.drugs.com/condition/obsessive-compulsive-disorder.html
Further Information
- Minocycline Information for Consumers
- Minocycline Information for Healthcare Professionals (includes dosage details)
- Side Effects of Minocycline (detailed)
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Hi, thanks for answering. Sorry I'm late in giving feedback. Minocycline has been given in multiple trials to people with OCD with amazing results. Seriously, results from research trials are usually never this good. As you know, medical science marches forward, but slowly. The clinical trials are still continuing but when news such as this gets out, some doctors may prescribe the medication to their patients since many meds can sometimes treat multiple symptoms. This time-tested and well known antibiotic in combination with Zoloft is worth checking out. So, the question really is: Has it been prescribed in private practice?
Minocycline has twenty identified anti-inflammatory actions documented in the the laboratory ( Savitz, Preskorn et al 2011). It is one of the few known anti-inflammatory medicines that penetrates the central nervous system. TLR inhibitor amitriptyline is okay at 10 mg po qhs for minor pain, headache prevention, and CNS inflammation; but at higher doses it has interactions with SSRI's and has numerous side effects. TLR inhibitor Naltrexone is effective at 50 mg po bid and usually is without side effects for anyone not taking an opiate - but a few people experience GI distress.
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Minocycline is a profound CNS anti-inflammatory and affects cranial circulation by reducing inflammation at the sutures as well as in the dura, cortex, and subcortical tissue. On minocycline it is hard to give yourself a headache with stress and over-work. The bone plates of the skull actually soften in two-to-three months and the brain resumes growth and normal osteopathic motion - called "motility". Every known condition of neurology and psychiatry has associated inflammation - with about 50% of the genes activated in the illness inflammatory. Every condition improves with minocycline.
Over half the psychiatric drugs being prescribed cause inflammation in the micro-glial cells of the brain. This is the real problem with opiates soothing neurons and irritating micro-glia. Microglial cells transform from being "nurse cells" into becoming killer white cells. The change is irreversibile. The brain, despite bathing three times a day (450 ml CSF replacing 150 ml three time) cannot get rid of the activated white cells, the toxic chemicals they secrete and the mess they make.
To be smart, take a probiotic every day if you plan on taking minocycline. Watch out for tinnitus, hearing changes, or unusual mental or neurological symptoms. You do not need to take minocycline every day to get anti-inflammatory benefit. Its use is so new we do not even know the limits of its benefit and whether continued treatment does anything once the inflammation in the brain comes down.
It doesn't take any fancy testing to tell if your head is hot. Put your hand on it. Compare your head to someone else. Slide your forehead around: does the bone move like shoe leather or is it rock-hard? The cooling will be palpably obvious with minocycline. The frontals tend to cool first, then the parietals.
One learns something new everyday, I just did today.
Thank you..